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1

Risk-based inspection and maintenance systems for steam turbines

Kazunari Fujiyama, Satoshi Nagai, Yasunari Akikuni, Toshihiro Fujiwara, Kenichiro Furuya, Shigeru Matsumoto, Kentaro Takagi, Taro Kawabata

Journal:

International Journal of Pressure Vessels and Piping

Year:

2004

Language:

english

File:

PDF, 1.15 MB

english, 2004

2

Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway

Mio Ikebe, Yoshiki Kitaura, Masafumi Nakamura, Haruo Tanaka, Akio Yamasaki, Shuntaro Nagai, Junji Wada, Kosuke Yanai, Kenichiro Koga, Norihiro Sato, Makoto Kubo, Masao Tanaka, Hideya Onishi, Mitsuo Ka

Journal:

Journal of Surgical Oncology

Year:

2009

Language:

english

File:

PDF, 229 KB

english, 2009

3

Bottromycin derivatives: Efficient chemical modifications of the ester moiety and evaluation of anti-MRSA and anti-VRE activities

Yutaka Kobayashi, Maki Ichioka, Tomoyasu Hirose, Kenichiro Nagai, Atsuko Matsumoto, Hidehiro Matsui, Hideaki Hanaki, Rokuro Masuma, Yoko Takahashi, Satoshi Ōmura, Toshiaki Sunazuka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 517 KB

english, 2010

4

γ-Secretase Inhibitors Enhance Taxane-Induced Mitotic Arrest and Apoptosis in Colon Cancer Cells

Takashi Akiyoshi, Masafumi Nakamura, Kosuke Yanai, Shuntaro Nagai, Junji Wada, Kenichiro Koga, Hiroshi Nakashima, Norihiro Sato, Masao Tanaka, Mitsuo Katano

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 3.16 MB

english, 2008

5

Mangromicins A and B: structure and antitrypanosomal activity of two new cyclopentadecane compounds from Lechevalieria aerocolonigenes K10-0216

Nakashima, Takuji, Iwatsuki, Masato, Ochiai, Junya, Kamiya, Yoshiyuki, Nagai, Kenichiro, Matsumoto, Atsuko, Ishiyama, Aki, Otoguro, Kazuhiko, Shiomi, Kazuro, Takahashi, Yōko, Ōmura, Satoshi

Journal:

The Journal of Antibiotics

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

6

Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase

Shibata, Norihito, Shimokawa, Kenichiro, Nagai, Katsunori, Ohoka, Nobumichi, Hattori, Takayuki, Miyamoto, Naoki, Ujikawa, Osamu, Sameshima, Tomoya, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.51 MB

english, 2018

7

Structure Determination and Total Synthesis of Bottromycin A2: A Potent Antibiotic against MRSA and VRE

Hiroyuki Shimamura, Hiroaki Gouda, Kenichiro Nagai, Tomoyasu Hirose, Maki Ichioka, Yujiro Furuya, Yutaka Kobayashi, Shuichi Hirono, Toshiaki Sunazuka, Satoshi Ōmura

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 374 KB

english, 2009

8

Structure Determination and Total Synthesis of Bottromycin A2: A Potent Antibiotic against MRSA and VRE

Hiroyuki Shimamura, Hiroaki Gouda, Kenichiro Nagai, Tomoyasu Hirose, Maki Ichioka, Yujiro Furuya, Yutaka Kobayashi, Shuichi Hirono, Toshiaki Sunazuka, Satoshi Ōmura

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 374 KB

english, 2009

9

ChemInform Abstract: Determination of Absolute Stereochemistries of Arisugacin F and Territrem B, Novel Acetylcholinesterase Inhibitors.

Masaki Handa, Toshiaki Sunazuka, Kenichiro Nagai, Ryouko Kimura, Kazuhiko Otoguro, Yoshihiro Harigaya, Satoshi Omura

Journal:

Year:

2001

File:

PDF, 28 KB

2001

10

ChemInform Abstract: Convergent Synthesis of Arisugacin Skeletons and Their Acetylcholinesterase Inhibitory Activity.

Masaki Handa, Toshiaki Sunazuka, Kenichiro Nagai, Ryouko Kimura, Tatsuya Shirahata, Zhi-Ming Tian, Kazuhiko Otoguro, Yoshihiro Harigaya, Satoshi Omura

Journal:

Year:

2001

File:

PDF, 32 KB

2001

11

ChemInform Abstract: The First Total Synthesis of (.+-.)-Arisugacin A, a Potent, Orally Bioavailable Inhibitor of Acetylcholinesterase.

Toshiaki Sunazuka, Masaki Handa, Kenichiro Nagai, Tatsuya Shirahata, Yoshihiro Harigaya, Kazuhiko Otoguro, Isao Kuwajima, Satoshi Omura

Journal:

Year:

2002

File:

PDF, 31 KB

2002

12

Synthesis and Biological Activities of Novel 4′′-Alkylidene Avermectin Derivatives.

Kenichiro Nagai, Toshiaki Sunazuka, Kazuro Shiomi, Achim Harder, Andreas Turberg, Satoshi Omura

Journal:

Year:

2004

File:

PDF, 202 KB

2004

13

Synthesis and Biological Evaluation of Novel 4′′-Alkoxy Avermectin Derivatives.

Kenichiro Nagai, Kazuro Shiomi, Toshiaki Sunazuka, Achim Harder, Andreas Turberg, Satoshi Omura

Journal:

Year:

2004

File:

PDF, 14 KB

2004

14

Absolute Stereochemistries and Total Synthesis of (+)-Arisugacins A and B, Potent, Orally Bioactive and Selective Inhibitors of Acetylcholinesterase.

Toshiaki Sunazuka, Masaki Handa, Kenichiro Nagai, Tatsuya Shirahata, Yoshihiro Harigaya, Kazuhiko Otoguro, Isao Kuwajima, Satoshi Omura

Journal:

Year:

2004

File:

PDF, 11 KB

2004

15

Macrolides with Promotive Activity of Monocyte to Macrophage Differentiation.

Kiminari Yoshida, Toshiaki Sunazuka, Kenichiro Nagai, Akihiro Sugawara, Achim Cho, Tohru Nagamitsu, Yoshihiro Harigaya, Kazuhiko Otoguro, Kiyoko S. Akagawa, Satoshi Omura

Journal:

Year:

2005

File:

PDF, 13 KB

2005

16

A camptothecin derivative from nothapodytes foetida

Ritsuo Aiyama, Hisako Nagai, Kenichiro Nokata, Chigiru Shinohara, Seigo Sawada

Journal:

Year:

1988

Language:

english

File:

PDF, 219 KB

english, 1988

17

Design and synthesis via click chemistry of 8,9-anhydroerythromycin A 6,9-hemiketal analogues with anti-MRSA and -VRE activity

Akihiro Sugawara, Toshiaki Sunazuka, Tomoyasu Hirose, Kenichiro Nagai, Yukie Yamaguchi, Hideaki Hanaki, K. Barry Sharpless, Satoshi Ōmura

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 165 KB

english, 2007

18

Synthesis and biological evaluation of a focused library of beauveriolides

Kenichiro Nagai, Takayuki Doi, Taichi Ohshiro, Toshiaki Sunazuka, Hiroshi Tomoda, Takashi Takahashi, Satoshi Ōmura

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 186 KB

english, 2008

19

Novel 12-membered non-antibiotic macrolides from erythromycin A; EM900 series as novel leads for anti-inflammatory and/or immunomodulatory agents

Akihiro Sugawara, Akito Sueki, Tomoyasu Hirose, Kenichiro Nagai, Hiroaki Gouda, Shuichi Hirono, Hideaki Shima, Kiyoko S. Akagawa, Satoshi Ōmura, Toshiaki Sunazuka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 411 KB

english, 2011

20

Synthesis of 4″-alkoxy avermectin derivatives using rhodium carbenoid-mediated O–H insertion reaction

Kenichiro Nagai, Toshiaki Sunazuka, Satoshi Ōmura

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 258 KB

english, 2004

21

Combination with corticosteroids and cyclosporin-A improves pulmonary function test results and chest HRCT findings in dermatomyositis patients with acute/subacute interstitial pneumonia

Takuya Kotani, Tohru Takeuchi, Shigeki Makino, Kenichiro Hata, Shuzo Yoshida, Koji Nagai, Daisuke Wakura, Takeshi Shoda, Toshiaki Hanafusa

Journal:

Clinical Rheumatology

Year:

2011

Language:

english

File:

PDF, 224 KB

english, 2011

22

Therapeutic drug monitoring of cyclosporine microemulsion in interstitial pneumonia with dermatomyositis

Koji Nagai, Tohru Takeuchi, Takuya Kotani, Kenichiro Hata, Shuzo Yoshida, Kentaro Isoda, Youhei Fujiki, Hideyuki Shiba, Shigeki Makino, Toshiaki Hanafusa

Journal:

Modern Rheumatology

Year:

2011

Language:

english

File:

PDF, 198 KB

english, 2011

23

Argifin; efficient solid phase total synthesis and evalution of analogues of acyclic peptide

Toshiaki Sunazuka, Akihiro Sugawara, Kanami Iguchi, Tomoyasu Hirose, Kenichiro Nagai, Yoshihiko Noguchi, Yoshifumi Saito, Tsuyoshi Yamamoto, Hideaki Ui, Hiroaki Gouda, Kazuro Shiomi, Takeshi Watanabe,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 672 KB

english, 2009

24

Synthesis and biological activities of novel 4″-alkylidene avermectin derivatives

Kenichiro Nagai, Toshiaki Sunazuka, Kazuro Shiomi, Achim Harder, Andreas Turberg, Satoshi Ōmura

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 154 KB

english, 2003

25

Synthesis and biological evaluation of novel 4″-alkoxy avermectin derivatives

Kenichiro Nagai, Kazuro Shiomi, Toshiaki Sunazuka, Achim Harder, Andreas Turberg, Satoshi Ōmura

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 289 KB

english, 2004

26

Absolute stereochemistries and total synthesis of (+)-arisugacins A and B, potent, orally bioactive and selective inhibitors of acetylcholinesterase

Toshiaki Sunazuka, Masaki Handa, Kenichiro Nagai, Tatsuya Shirahata, Yoshihiro Harigaya, Kazuhiko Otoguro, Isao Kuwajima, Satoshi Ōmura

Journal:

Year:

2004

Language:

english

File:

PDF, 358 KB

english, 2004

27

Macrolides with Promotive Activity of Monocyte to Macrophage Differentiation

Yoshida, Kiminari, Sunazuka, Toshiaki, Nagai, Kenichiro, Sugawara, Akihiro, Cho, Achim, Nagamitsu, Tohru, Harigaya, Yoshihiro, Otoguro, Kazuhiko, Akagawa, Kiyoko S., Ōmura, Satoshi

Journal:

The Journal of Antibiotics

Year:

2005

Language:

english

File:

PDF, 85 KB

english, 2005

28

4″′-N-Demethylspiramycin Derivatives: Synthesis and Evaluation of Effectiveness against Drug-resistant Bacteria

Sunazuka, Toshiaki, Shudo, Hiroko, Nagai, Kenichiro, Yoshida, Kiminari, Yamaguchi, Yukie, Hanaki, Hideaki, Ōmura, Satoshi

Journal:

The Journal of Antibiotics

Year:

2008

Language:

english

File:

PDF, 222 KB

english, 2008

29

Total Synthesis of Malformin C, an Inhibitor of Bleomycin-Induced G2 Arrest

Kojima, Yasuhiro, Sunazuka, Toshiaki, Nagai, Kenichiro, Julfakyan, Khachatur, Fukuda, Takashi, Tomoda, Hiroshi, Ōmura, Satoshi

Journal:

The Journal of Antibiotics

Year:

2008

Language:

english

File:

PDF, 152 KB

english, 2008

30

Solid-phase synthesis and biological activity of malformin C and its derivatives

Kojima, Yasuhiro, Sunazuka, Toshiaki, Nagai, Kenichiro, Hirose, Tomoyasu, Namatame, Miyuki, Ishiyama, Aki, Otoguro, Kazuhiko, Ōmura, Satoshi

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 416 KB

english, 2009

31

Characterization of Cobalt Molybdenum Nitrides for Thiophene HDS by XRD, TEM, and XPS

Kenichiro Hada, Junko Tanabe, Shinzo Omi, Masatoshi Nagai

Journal:

Journal of Catalysis

Year:

2002

Language:

english

File:

PDF, 550 KB

english, 2002

32

Expression pattern of a newly recognized protein, LECT2, in hepatocellular carcinoma and its premalignant lesion

Toshikazu Uchida, Hisakazu Nagai, Kenichiro Gotoh, Hiroshi Kanagawa, Harukazu Kouyama, Teruaki Kawanishi, Satoaki Mima, Satoshii Yamagoe, Kazuo Suzuki

Journal:

Pathology International

Year:

1999

Language:

english

File:

PDF, 269 KB

english, 1999

33

THYROID GLAND METASTASIS FROM RENAL CELL CARCINOMA MASQUERADING AS NODULAR GOITRE

Hideaki Niiyama, Koji Yamaguchi, Eishi Nagai, Kenichiro Furukawa, Motomichi Torisu, Masao Tanaka

Journal:

ANZ Journal of Surgery

Year:

1994

Language:

english

File:

PDF, 882 KB

english, 1994

34

XPS and TPR Studies of Nitrided Molybdena−Alumina

Hada, Kenichiro, Nagai, Masatoshi, Omi, Shinzo

Journal:

Journal of Physical Chemistry B

Year:

2000

Language:

english

File:

PDF, 290 KB

english, 2000

35

Two-Year Visual Results for Older Asian Women Treated With Photodynamic Therapy or Bevacizumab for Myopic Choroidal Neovascularization

Yasushi Ikuno, Yoshimi Nagai, Satoshi Matsuda, Akiko Arisawa, Kenichiro Sho, Takashi Oshita, Kanji Takahashi, Yasutaka Uchihori, Fumi Gomi

Journal:

American Journal of Ophthalmology

Year:

2010

Language:

english

File:

PDF, 839 KB

english, 2010

36

Reply

Yasushi Ikuno, Yoshimi Nagai, Satoshi Matsuda, Akiko Arisawa, Kenichiro Sho, Takashi Oshita, Kanji Takahashi, Yasutaka Uchihori, Fumi Gomi

Journal:

American Journal of Ophthalmology

Year:

2010

Language:

english

File:

PDF, 292 KB

english, 2010

37

Crosstalk of hedgehog and Wnt pathways in gastric cancer

Kosuke Yanai, Masafumi Nakamura, Takashi Akiyoshi, Shuntaro Nagai, Junji Wada, Kenichiro Koga, Hirokazu Noshiro, Eishi Nagai, Masazumi Tsuneyoshi, Masao Tanaka, Mitsuo Katano

Journal:

Year:

2008

Language:

english

File:

PDF, 438 KB

english, 2008

38

In vivo adenovirus-mediated HGF gene transfer reduces myocardial infarct size in rabbits

Xue-Hai Chen, Shinya Minatoguchi, Kenichiro Kosai, Kentaro Yuge, Minoru Nagano, Tomoyuki Takahashi, Masazumi Arai, Ningyuan Wang, Yu Misao, Chuanjiang Lu, Yoji Nagai, Genzou Takemura, Takako Fujiwara,

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 227 KB

english, 2002

39

(±)-Tylopilusins, Diphenolic Metabolites from the Fruiting Bodies of Tylopilus eximius

Fukuda, Takashi, Nagai, Kenichiro, Tomoda, Hiroshi

Journal:

Journal of Natural Products

Year:

2012

Language:

english

File:

PDF, 602 KB

english, 2012

40

Prevalence of Gastro-Esophageal Reflux Disease Symptoms in General Practice

Yoshihisa Urita, Susumu Ishihara, Kenichiro Arai, Jun Kondo, Tatsuo Akimoto, Hiroto Kato, Yoshiko Honda, Hideyuki Koshino, Noriko Hara, Yoko Nagai, Kazushige Nakanishi, Nagato Shimada, Motonobu Sugimo

Journal:

Gastrointestinal Endoscopy

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

41

Synthesis and antimycobacterial activity of calpinactam derivatives

Nagai, Kenichiro, Koyama, Nobuhiro, Sato, Noriko, Yanagisawa, Chisato, Tomoda, Hiroshi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 221 KB

english, 2012

42

The First Total Synthesis of (±)-Arisugacin A, a Potent, Orally Bioavailable Inhibitor of Acetylcholinesterase

Sunazuka, Toshiaki, Handa, Masaki, Nagai, Kenichiro, Shirahata, Tatsuya, Harigaya, Yoshihiro, Otoguro, Kazuhiko, Kuwajima, Isao, Ōmura, Satoshi

Journal:

Organic Letters

Year:

2002

Language:

english

File:

PDF, 59 KB

english, 2002

43

Absolute Stereochemistry of Fungal Beauveriolide III and ACAT Inhibitory Activity of Four Stereoisomers

Ohshiro, Taichi, Namatame, Ichiji, Nagai, Kenichiro, Sekiguchi, Takafumi, Doi, Takayuki, Takahashi, Takashi, Akasaka, Kazuaki, Rudel, Lawrence L., Tomoda, Hiroshi, Ōmura, Satoshi

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 334 KB

english, 2006

44

Efficacy and safety of liposomal amphotericin B for deep mycosis in patients with connective tissue disease

Kotani, Takuya, Takeuchi, Tohru, Makino, Shigeki, Hata, Kenichiro, Yoshida, Shuzo, Nagai, Koji, Wakura, Daisuke, Isoda, Kentaro, Hanafusa, Toshiaki

Journal:

Journal of Infection and Chemotherapy

Year:

2013

Language:

english

File:

PDF, 196 KB

english, 2013

45

Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change

Yamagata, Kenichiro, Goto, Yuki, Nishimasu, Hiroshi, Morimoto, Jumpei, Ishitani, Ryuichiro, Dohmae, Naoshi, Takeda, Norihiko, Nagai, Ryozo, Komuro, Issei, Suga, Hiroaki, Nureki, Osamu

Journal:

Year:

2014

Language:

english

File:

PDF, 2.69 MB

english, 2014

46

Epimorphin, a novel stellate cell-derived protein, induces not only hepatocytic differentiation but also cholangiocytic differentiation of rat hepatic stem-like cells

Miura, Kouichi, Goto, Takashi, Mikami, Kenichiro, Nakane, Kunio, Yoneyama, Kazuo, Lin, Jiun-Guey, Watanabe, Daisuke, Nagai, Hirokazu, Terada, Kunihiko, Imai, Katsuyuki, Senoo, Haruhiko, Sugiyama, Tosh

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 256 KB

english, 2003

47

Characterization and HDS Activity of Cobalt Molybdenum Nitrides

Hada, Kenichiro, Nagai, Masatoshi, Omi, Shinzo

Journal:

Journal of Physical Chemistry B

Year:

2001

Language:

english

File:

PDF, 352 KB

english, 2001

48

Absolute Stereochemistry of Fungal Beauveriolide III and ACAT Inhibitory Activity of Four Stereoisomers.

Ohshiro, Taichi, Namatame, Ichiji, Nagai, Kenichiro, Sekiguchi, Takafumi, Doi, Takayuki, Takahashi, Takashi, Akasaka, Kazuaki, Rudel, Lawrence L., Tomoda, Hiroshi, Ōmura, Satoshi

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 19 KB

english, 2006

49

Synthesis and Biological Evaluation of a Beauveriolide Analogue Library

Nagai, Kenichiro, Doi, Takayuki, Sekiguchi, Takafumi, Namatame, Ichiji, Sunazuka, Toshiaki, Tomoda, Hiroshi, Ōmura, Satoshi, Takahashi, Takashi

Journal:

Journal of Combinatorial Chemistry

Year:

2006

Language:

english

File:

PDF, 119 KB

english, 2006

50

Electronic Spectra of Two Long-Lived Photoproducts: Double-Proton Transfer in 7-Hydroxyquinoline Dimer in a 2-Methyltetrahydrofuran Glass Matrix

Nagai, Yuko, Saita, Kenichiro, Sakota, Kenji, Nanbu, Shinkoh, Sekine, Masahiko, Nakata, Munetaka, Sekiya, Hiroshi

Journal:

Journal of Physical Chemistry A

Year:

2010

Language:

english

File:

PDF, 1.37 MB

english, 2010

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